It messed with DNS resolution for my local network, at least temporarily. I couldn’t resolve any websites that needed to hit our local DNS server. I did some Googling and saw that the resolver tech was changed from Fedora 32 to Fedora 33. I change a setting for my NIC and then changed it back and either that fixed it or (some websites mentioned just needing to give it some time). Either way, that was it. Relatively smooth.